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  • Title: [Relapsing childhood digital fibromatosis. Study of a case with electron and light microscopy and review of the literature].
    Author: Rodriguez G, Rueda LA.
    Journal: Med Cutan Ibero Lat Am; 1975; 3(2):111-8. PubMed ID: 1240564.
    Abstract:
    The first Latin-American case of a relapsing digital fibromatosis in a 6 months old child is presented by the authors. With the H.E. staining cytoplasmatic inclusions were found in the fibroblasts. For the first time the presence of cellular synctitiums in the entity is described. Many of these synctitiums contain inclusion bodies. This inclusion observed with electron microscope was constituted by a considerable amount of filaments condensing in the center and the well developed stages occupying most of the cyloplasm. No viral particles were found. The accumulation of filaments in the fibroblast causes a degenerative final stage of the cells. The possibility whether this inclusion represents an accumulation of the synthetised fibers by the fibroblast or a conglomerate is not determined by this study. An extensive review of the literature on this subject is made by the authors.
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