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  • Title: Clinical outcomes in juvenile dermatomyositis.
    Author: Ramanan AV, Feldman BM.
    Journal: Curr Opin Rheumatol; 2002 Nov; 14(6):658-62. PubMed ID: 12410087.
    Abstract:
    Juvenile dermatomyositis is a chronic inflammatory illness of unknown etiology that affects primarily muscle and skin. It has an incidence of 2-3 per 1,000,000, per year. The disease can affect other organ systems, including the gastrointestinal tract, lungs, and heart. In addition, calcinosis is seen in one-third of patients. The mainstay of therapy is corticosteroids; some children require additional immunosuppressive agents because of corticosteroid resistance or intolerance. Functional outcomes have become good with modern treatments, but the disease remains chronic in a large number of children and sequelae are often seen.
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