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  • Title: Antibodies in human filariasis sera react with diethylcarbamazine.
    Author: Ravindran B, Satapathy AK, Hussain T, Pattnaik AM.
    Journal: Clin Exp Immunol; 1989 Nov; 78(2):219-23. PubMed ID: 12412752.
    Abstract:
    We demonstrate by an ELISA the presence of antibodies in human filarial sera that react with diethylcarbamazine (DEC); they appear to be primarily filarial antibodies cross-reacting with DEC skeleton, since affinity-purified DEC antibodies strongly react with Wuchereria bancrofti microfilariae. These observations indicate a possible antigenic mimicry between the drug and some parasite component.
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