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  • Title: [Success in a case of fulminant hepatitis treated with extracorporeal liver perfusion and exchange transfusion].
    Author: Scopinaro N, Anfossi A, Griffanti-Bartoli F, Civalleri D, Sorice G, Bonalumi U, Caponnetto A, Bachi V.
    Journal: Minerva Chir; 1975 Mar 15; 30(5):271-6. PubMed ID: 1241607.
    Abstract:
    Extracorporeal perfusion of pig liver lasting 4 hr, followed by isovolaemic exchange (6 litres in 1 hr) were employed in the management of coma in a case of acute virus hepatitis. Liver perfusion led to temporary regression of coma, whereas transfusion was followed by gradual improvement in the clinical picture; this was apparently not a direct consequence of the procedure adopted. Assessment of the degree of purification obtained with these two methods offers an explanation for the difference in their clinical effectiveness.
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