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  • Title: [Current perspectives in the treatment of Huntington's chorea].
    Author: Kuran W.
    Journal: Neurol Neurochir Pol; 2002; 36(4):757-65. PubMed ID: 12418139.
    Abstract:
    Huntington's chorea (HD) is a degenerative condition of the central nervous system of genetic origin, inherited as an autosomal dominant trait. The mechanism of the genetic defect is already known, it is a dynamic mutation in the ITI5 gene situated on chromosome 4 p 16.3 coding the protein huntington. The disease is progressive and leading to lethal outcome and effective treatment is unknown. Methods of treatment of various disturbances developing in this disease are described with stress laid on neuroprotective methods which could perhaps give better results in not so far future.
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