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  • Title: Importance of screening the peripheral smear.
    Author: Rajajee S, Sathyasekaran M, Shankar J, Dhathathri L, Anandnathan.
    Journal: Indian J Pediatr; 2002 Sep; 69(9):821-2. PubMed ID: 12420918.
    Abstract:
    A 5-year-old boy presented with history of failure to thrive from infancy. There was a history of one sibling death due to similar problems and history of severe abortions in the mother. Routine examination of peripheral smear revealed more than 50% acanthocytes. Based on this tests were streamlined to doing lipid profile and Lipo protein electrophoresis which revealed hypolipidemia and absent beta hypo protein band. Jejunal mucosal biopsy confirmed the diagnosis of A Beta Lipo proteinemia which revealed lipid laden enterocytes. This case illustrates the importance of simple tests like peripheral smear examination in streamlining further tests in the diagnosis of major diseases.
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