These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Animal experiments on the "dysionic genesis of intrauterine malformations"].
    Author: Gödde VE, Grote W.
    Journal: Arzneimittelforschung; 1975 May; 25(5):809-13. PubMed ID: 1242330.
    Abstract:
    Pregnant rabbits were injected 12 mg 4-chloro-5-sulfamoyl-N-furfuryl-anthranilic acid (furosemide)/kg body weight from the first to the tenth day of pregnancy (o.p.). The serum concentrations of sodium, potassium and calcium were determined on the 1st, 9th and 14th day o.p. The mother rabbits were killed on the 29th day of o.p., their foetuses were removed and the mucous membrane of the uterus was inspected for resorption sites. The foetuses were examined, the skeletons were stained and studied under the microscope. The results of the treated rabbits were compared with those of the control rabbits. The sodium, potassium and calcium concentrations of the treated rabbits were not lowered significantly. The haematocrite did not change during or after the treatment. The mothers gained weight continuously. The rates of resorption and malformation of the treated group were slightly raised.
    [Abstract] [Full Text] [Related] [New Search]