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  • Title: The effects of dexamethasone and starvation on body composition and regional adipose tissue cellularity in the rat.
    Author: Krotkiewski M, Björntorp P.
    Journal: Acta Endocrinol (Copenh); 1975 Dec; 80(4):667-75. PubMed ID: 1242576.
    Abstract:
    In order to examine regional effects of corticosteroids on the depot fat distribution a dose of dexamethasone that produced changes in fat cell weight (40 mug per kg per day) was administered to rats. Starved rats were included for comparison. Starvation caused a decrease in depot fat and fat cell weight proportional to the characteristic fat cell weight of that region. In comparison with the changes found in the depots of pair-fed rats the effects of dexamethasone in this dose were largely the same. The epididymal adipocytes behaved differently and were emptied more slowly than their weight indicated.
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