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  • Title: Synthesis and pharmacological studies of some 2-t-amino and 2,3-di-t-amino substituted 1,4-naphthoquinones and related compounds.
    Author: Tandon VK, Singh RV, Rai S, Chhor RB, Khan ZK.
    Journal: Boll Chim Farm; 2002; 141(4):304-10. PubMed ID: 12426819.
    Abstract:
    Series of 2-t-amino and 2,3-di-t-amino substituted-1,4-naphthoquinones have been synthesised from corresponding 1,4-naphthoquinones by reaction with secondary amines. The compounds have been evaluated for their broad spectrum antimicrobial, antiviral and anticancer activity. In the preliminary screening results 8a and 9a have shown profile of an antimicrobial agent.
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