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  • Title: cDNA cloning and mRNA expression of Transformer 2 (Tra 2) in chicken embryo.
    Author: Yamamoto I, Tsukada A, Saito N, Shimada K.
    Journal: Biochim Biophys Acta; 2002 Dec 12; 1579(2-3):185-8. PubMed ID: 12427554.
    Abstract:
    We report the cloning of a chicken Transformer 2 (Tra 2) cDNA that encodes a protein of 289 amino acids which are 97.9% identical to those of mammalian splicing factor, Tra 2. Tra 2 mRNA was expressed in chicken embryonic tissues and was observed as a band of 1.5 kb by Northern blot analysis. Whole mount in situ hybridization showed an mRNA expression of Tra 2 in telencephalon, mandible, hyoid arch, wing and leg buds as early as day 3.5 of incubation. These results suggest that the Tra 2 gene may play a role in organogenesis in the chicken embryo.
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