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  • Title: Sensitization of trigeminal nociception specific for migraine but not pain of sinusitis.
    Author: Katsarava Z, Lehnerdt G, Duda B, Ellrich J, Diener HC, Kaube H.
    Journal: Neurology; 2002 Nov 12; 59(9):1450-3. PubMed ID: 12427905.
    Abstract:
    Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age- and sex-matched patients with comparable unilateral headache from frontal sinusitis. Using a nociception-specific blink reflex method (nBR), a facilitation of nBR responses predominantly on the headache side was observed in migraine, but not in sinusitis. The facilitation of trigeminal nociception may be specific for migraine rather than a consequence of peripheral pain such as frontal sinusitis.
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