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Title: Relation between structure and cholinergic activity. II. Synthesis and muscarinic activity of some sulfur analogs of 2-methyl-4-trimethylammoniomethyl-1,3-dioxolane-iodide. Author: Elferink JG, Salemink CA. Journal: Arzneimittelforschung; 1975 Nov; 25(11):1702-5. PubMed ID: 1243076. Abstract: The synthesis of 2-methyl-5-trimethylammoniomethyl-1,3-oxathiolane and some homologs are described. The stereochemical aspects are discussed on the basis of the NMR-spectra. The muscarinic activity of the oxathiolane is compared with the activities of the corresponding dioxolane and dithiolane.[Abstract] [Full Text] [Related] [New Search]