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  • Title: [Diagnosis of hepatocellular carcinoma with bone metastasis using fine needle aspiration biopsy: report of 2 cases].
    Author: Dan HL, Zhao Y, Zhang YL, Yu L, Zhang JR, Zhang ZS.
    Journal: Di Yi Jun Yi Da Xue Xue Bao; 2002 Nov; 22(11):978-80. PubMed ID: 12433621.
    Abstract:
    The clinical presentations and imaging characteristics of hepatocellular carcinoma (HCC) are usually various and complex. This article reported 2 cases of HCC with the initial symptoms being bone metastasis that did not exhibit typical clinical manifestations or distinct feature in liver imaging, without elevated serum alpha-fetoprotein. The diagnoses were certified by fine needle aspiration biopsy, which is recommended for differential diagnosis in cases of complex HCC with bone metastasis, to avoid liver biopsy and surgical bone biopsy.
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