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  • Title: Extraventricular neurocytoma: morphological and immunohistochemical considerations on differential diagnosis.
    Author: Buccoliero AM, Caldarella A, Ammannati F, Mennonna P, Taddei A, Taddei GL.
    Journal: Pathol Res Pract; 2002; 198(9):627-33; discussion 635-8. PubMed ID: 12440786.
    Abstract:
    Neurocytoma is an unusual neuronal tumor especially affecting young people. It commonly arises in the ventricles and has a benign outcome. Herein, we report on a rare case of extraventricular neurocytomas (right parietal lobe) in a young girl admitted to hospital for a cranial trauma subsequent to a seizure. The tumor, radiologically well-circumscribed, cystic and enhancing, was surgically excised. The patient, who received no post surgical treatment, is alive and well after 18 months of follow-up. Pathological examination showed a well-differentiated lesion composed of uniform, round cells with perinuclear halos in a neuropil background and immunohistochemically positive for neuronal markers (synaptophysin, neuron-specific enolase, neurofilaments). The authors emphasize the role of the morphological and immunohistochemical evaluations to recognize this rare tumor.
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