These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Activation of tryptophan pyrrolase by benzylhydrazine.
    Author: Satoh T.
    Journal: Acta Vitaminol Enzymol; 1975; 29(1-6):283-6. PubMed ID: 1244108.
    Abstract:
    The mechanism responsible for the activation of tryptophan pyrrolase (TP) by benzylhydrazine (BZH) was investigated. The increase in holo/apo ratio of rat TP activity after addition of BZH in concentration of 1 x 10(-4)M, which is a major metabolite of isocarboxazid (ISOC), was higher than those in mice and guinea pigs. In addition, treatment with ISOC to rats (50 mg/kg i.p.) resulted in a significant increase in TP activity. These results suggested that the BZH-induced elevation of TP is at least in part due to a stimulation of conjugation step of TP activity.
    [Abstract] [Full Text] [Related] [New Search]