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  • Title: Metabolic effects of weight reduction in obese diabetics and nondiabetics.
    Author: Julius U, Schneider H, Leonhardt W, Hanefeld M, Gabsch HC.
    Journal: Endokrinologie; 1976 Mar; 67(1):96-102. PubMed ID: 1244205.
    Abstract:
    A weight loss of about 10 kg was acheived by means of individual periods of total fasting, hypocaloric diets and physical activity in three groups of patients: maturity-onset diabetics, patients with pathological OGTT and overweight persons with normal OGTT. Adipocyte volume decreased in all groups, glucose tolerance improved. IRI curves showed a significant overall lowering and FFA concentrations during OGTT were dimished.
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