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  • Title: Heart defects and ocular anomalies in children with Down's syndrome.
    Author: Bromham NR, Woodhouse JM, Cregg M, Webb E, Fraser WI.
    Journal: Br J Ophthalmol; 2002 Dec; 86(12):1367-8. PubMed ID: 12446367.
    Abstract:
    AIMS: To investigate whether ocular anomalies are associated with congenital heart defects in children with Down's syndrome. METHODS: 58 children with Down's syndrome were entered into a retrospective observational study. Children were assigned to heart defect groups based on medical records. Optometric tests had previously been carried out at the homes of the children. RESULTS: A relation between congenital cardiac defects, myopia, and nystagmus was observed. Heart problems were not related to accommodative insufficiency, hyperopia, or strabismus. CONCLUSION: In children with Down's syndrome heart defects were associated with both myopia and nystagmus.
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