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  • Title: Acute haemorrhagic oedema of infancy associated with cytomegalovirus infection.
    Author: Kuroda K, Yabunami H, Hisanaga Y.
    Journal: Br J Dermatol; 2002 Dec; 147(6):1254-7. PubMed ID: 12452880.
    Abstract:
    Acute haemorrhagic oedema (AHO) of infancy is a cutaneous leukocytoclastic vasculitis, clinically characterized by the acute development of peripheral oedema and targetoid purpuric lesions on the face and extremities. It usually affects children younger than 2 years of age. The disorder follows a benign course usually without recurrence or long-term complication. In most cases the origin is not clear, but underlying infections are assumed to play an aetiological role. We describe a 7-month-old boy whose clinical and histopathological features are typical of AHO. Serological tests clearly demonstrated a primary infection for cytomegalovirus (CMV). To our knowledge, this is the first reported case of AHO associated with CMV infection.
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