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  • Title: Resistance to macrolides in Group A streptococci from the European section of Turkey: genetic and phenotypic characterization.
    Author: Akata F, Oztürk D, Tansel O, Tatman-Otkun M, Otkun M, Fitoussi F, Bingen E, Tugrul M.
    Journal: Int J Antimicrob Agents; 2002 Dec; 20(6):461-3. PubMed ID: 12458142.
    Abstract:
    The aim of this study was to determine the susceptibilities to macrolides of Group A streptococcal isolates from the European section of Turkey. In the case of resistant isolates, the patterns and genetic mechanisms of erythromycin resistance were studied. Seven (2.7%) of the 260 isolates were resistant to erythromycin. Four of them showed the M phenotype and harboured mefA genes whereas three isolates showed the inducible macrolide, lincosamide and streptogramin B resistance phenotype and harboured ermTR genes. In the European section of Turkey, the current resistance rate of Group A streptococci to macrolides remains low.
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