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  • Title: Hemopoietic and lymphoid organs in AKR/JY mice with thymic lymphoma.
    Author: Karpova GV, Fomina TI, Abramova EV, Bel'skaya NV, Trofimova ES, Perel'muter VM.
    Journal: Bull Exp Biol Med; 2002 Jul; 134(1):69-72. PubMed ID: 12459873.
    Abstract:
    Cytological and histological studies of the thymus, bone marrow, peripheral blood, spleen, and lymph nodes in 6-9-month-old AKR/JY mice showed that the risk of thymic lymphoma in these animals increased with age. Generalization of the tumor process was observed in mice aged over 8 months and first involved the spleen, then the lymph nodes, bone marrow, and liver. A case of primary lymphoma in the spleen was detected.
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