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  • Title: [A clinical study on composite transplantation of meshed split-thickness autograft and heterologous dermal matrix].
    Author: Feng X, Tan J, Du Y, Ruan S, Pan Y.
    Journal: Zhonghua Zheng Xing Wai Ke Za Zhi; 2002 Sep; 18(5):269-70. PubMed ID: 12471812.
    Abstract:
    OBJECTIVE: To investigate the feasibility of the composite transplantation of 1:3 meshed split-thickness autograft and acellular heterologous (porcine) dermal matrix. METHODS: 9 inpatients with full thickness skin burn or hypertrophic scar were selected in this study. After the eschar or scar was excised, the wound was covered with acellular heterologous dermal matrix. Then the meshed (1:3) split-thickness autologous skin sheet was grafted on the dermal matrix. Before dressing up, the radiated pigskin was placed on the composite transplants. RESULTS: The composite transplantation was successfully used in 9 cases. The meshed split-thickness autograft was expanded 3 times and covered the dermal matrix tightly. The clinical results of the composite transplantation were similar to that of intermediate split thickness skin graft or full thickness skin graft. CONCLUSION: The composite transplantation of meshed (1:3) split-thickness autograft and acellular heterologous (porcine) dermal matrix allowed the expansion of the autologous skin sheet to 3 times. The clinical results were similar to that of intermediate split thickness skin graft or full thickness skin graft.
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