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  • Title: Sodium ion transport in isolated intestinal epithelial cells. II. Comparison of the effect of actively transported sugars on sodium ion efflux in cells isolated from jejunum and ileum.
    Author: Gall DG, Chapman D.
    Journal: Biochim Biophys Acta; 1976 Jan 21; 419(2):314-9. PubMed ID: 1247558.
    Abstract:
    Na+ transport studies in intestinal epithelial cells indicate that enterocytes from different regions of the small intestine differ in their response to actively transported sugars. 1. Compared with sugar-free medium total Na+ efflux rate constants from isolated rat jejunal cells were significantly increased when medium contained actively transported sugars, glucose and galactose, but not when medium contained fructose. 2 In contrast total Na+ efflux rate constants from isolated rat ileal cells did not respond to actively transported sugars, glucose and galactose. 3. Similar results for the effect of actively transported sugars on Na+ ellux were obtained for isolated rabbit jejunal and ileal epithelial cells. 4. Passive Na+ efflux rate constants for isolated jejunal and ileal enterocytes are not significantly different, indicating similiar permeability characteristics.
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