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Title: Precision and accuracy of a HPLC method for measurement of fecal porphyrin concentrations. Author: Zuijderhoudt FM, Kamphuis JS, Kluitenberg WE, Dorresteijn-de Bok J. Journal: Clin Chem Lab Med; 2002 Oct; 40(10):1036-9. PubMed ID: 12476945. Abstract: We studied precision and accuracy of a HPLC method for determination of porphyrins in feces. A commercial standard solution appeared to contain less coproporphyrin (15%) than stated by the manufacturer. The between-batch coefficients of variation were often below 15% and were higher than the within-batch coefficients. The precision of porphyrin measurements was not influenced by the type of porphyria. Recoveries of added coproporphyrin and protoporphyrin were 90% and 108%; coefficients of variation were 6% and 19%, respectively.[Abstract] [Full Text] [Related] [New Search]