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  • Title: Epithelioid trophoblastic tumor of the endocervix: a case report.
    Author: Meydanli MM, Kucukali T, Usubutun A, Ataoglu O, Kafkasli A.
    Journal: Gynecol Oncol; 2002 Nov; 87(2):219-24. PubMed ID: 12477457.
    Abstract:
    BACKGROUND: It is difficult to recognize epithelioid trophoblastic tumor (ETT) as a trophoblastic disease because of its rarity and growth pattern simulating a carcinoma. CASE REPORT: A 36-year-old woman with stage IB(1) squamous cell carcinoma of the uterine cervix and a high serum beta-human chorionic gonadotropin (beta-hCG) level underwent radical hysterectomy with pelvic and para-aortic lymphadenectomy. However, light microscopic findings and immunohistochemical studies with pan-cytokeratin, epithelial membrane antigen, inhibin-alpha, beta-hCG, and human placental lactogen revealed ETT of the endocervix. The patient is alive with no evidence of disease 12 months after surgery. CONCLUSION: Before the patient is resorted to radical surgical interventions for assumed cervical carcinoma, ETT should be ruled out in women of reproductive age with endocervical tumors and elevated serum beta-hCG levels.
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