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  • Title: Hepatitis agents with enteric transmission--an epidemiological analysis.
    Author: Yayli G, Kiliç S, Ormeci AR.
    Journal: Infection; 2002 Dec; 30(6):334-7. PubMed ID: 12478320.
    Abstract:
    BACKGROUND: Viral hepatitis is characterized by special clinical, biochemical and serological findings. This study was planned to determine the seroprevalence, epidemiological characteristics and clinical and biochemical findings of hepatitis A virus (HAV) and hepatitis E virus (HEV) infections during an outbreak of jaundice. MATERIALS AND METHODS: 340 children aged 5-16 years were included. Clinical findings and alanine aminotransferase (ALT) levels were documented. Anti-HAV IgG and IgM in addition to anti-HEV IgG and IgM were determined by microELISA. RESULTS: Clinical findings, high levels of ALT, anti-HAV IgM and IgG, anti-HEV IgM and IgG were present in 6%, 23%, 17%, 100%, 7% and 9% of cases, respectively. The relationship between ALT levels and anti-HAV or anti-HEV IgM seropositivity was significant (p </= 0.0001). CONCLUSION: HAV and HEV infection were both caused by a contaminated water supply.
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