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Title: Affinity labeling of the nuclear vitamin D receptor with nonsteroidal alkylating agents. Author: Fernández-Gacio A, Fernández-Marcos C, Swamy N, Ray R. Journal: Bioorg Med Chem Lett; 2003 Jan 20; 13(2):213-6. PubMed ID: 12482426. Abstract: Synthesis of an affinity alkylating non steroidal mimic of 1alpha,25-dihydroxyvitamin D(3) and its radiolabeled counterpart is presented. We also report the affinity labeling of the VDR-ligand binding domain (VDR-LBD) with this analogue.[Abstract] [Full Text] [Related] [New Search]