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  • Title: Incidental diagnosis and tempestive therapy in a case of neonatal alloimmune thrombocytopenia due to anti-HPA-5b.
    Author: Zuppa AA, Cota F, De Luca D, Visintini F, De Turris PL, Tortorolo G.
    Journal: Pediatr Hematol Oncol; 2002 Dec; 19(8):587-91. PubMed ID: 12487835.
    Abstract:
    Neonatal alloimmune thrombocytopenia (NAIT) is usually attributable to HPA-1a antibodies. The authors report a case of incidentally diagnosed thrombocytopenia in a small for gestational age infant. A NAIT was suspected and she was successfully treated with intravenous IgG. The direct and indirect platelet suspension immunofluorescence test (PSIFT) in maternal blood suggested alloimmunization to HPA-5b. Empiric treatment with IgG could be useful in case of clear suspect even in absence of confirmed diagnosis.
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