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  • Title: Effect of dietary protein and tryptophan and the turnover of rat liver ornithine aminotransferase.
    Author: Chee PY, Swick RW.
    Journal: J Biol Chem; 1976 Feb 25; 251(4):1029-34. PubMed ID: 1249066.
    Abstract:
    Under controlled conditions of diet, age, and animal management we confirmed our earlier studies that the fractional turnover rate constant of rat liver ornithine aminotransferase (L-ornithine:2-oxoacid aminotransferase, EC 2.6.1.13) was about 0.4 day-1 when estimated by tracer technique. However, when estimated by the kinetics of enzyme activity perturbation during dietary induction or return to normal levels, a value of about 0.7 day-1 was obtained. This discrepancy may now be attributed in part to a transistory change in the fractional rate constant during enzyme adaption.
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