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  • Title: Moving across membranes.
    Author: Neale EA.
    Journal: Nat Struct Biol; 2003 Jan; 10(1):2-3. PubMed ID: 12490883.
    Abstract:
    Protein toxins are known to translocate through intracellular membranes to reach their cytosolic targets. Results from studies with botulinum neurotoxin suggest that the toxin heavy chain functions as both a channel and a chaperone for translocation of the catalytically active light chain.
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