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  • Title: IgA nephropathy in a patient with chronic granulomatous disease.
    Author: Narsipur SS, Shanley PF.
    Journal: J Nephrol; 2002; 15(6):713-5. PubMed ID: 12495290.
    Abstract:
    We report the first documented case of X-linked chronic granulomatous disease (CGD) in association with IgA nephropathy in a 22 year old male with multiple soft tissue abscesses. The case highlights the potential role of staphylococcal infections in the pathogenesis of IgA nephropathy and suggests the hypothesis that the neutrophil defect in CGD predisposes to such infections which may trigger IgA immune complex formation.
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