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  • Title: [Chronic pericarditis in Hodgkin disease].
    Author: Miltényi Z, Gergely L, Illés A.
    Journal: Orv Hetil; 2002 Dec 01; 143(48):2687-9. PubMed ID: 12501578.
    Abstract:
    INTRODUCTION: Among late complications of Hodgkin's disease's treatment the cardiovascular complications are important. The incidence of the late onset (later than 48 months) of chronic pericardial disease is from 11 to 50% among patients with Hodgkin's disease with irradiation in the past history. PURPOSE AND METHODS: Authors are presenting chronic constrictive pericarditis in a case among late consequences of therapy of Hodgkin's disease. It's difficult to observe and treat, because it's a rarity. RESULTS (CASE REPORT): A male patient, who is 35 year old in the present, developed III/A2 clinical stage, mixed cellularity Hodgkin's disease in 1992. He got combined chemotherapy and irradiation repeated and he came to complete remission. In 1999 he had no symptoms, but the physical examination, routine chest radiography and echocardiography proved pericardial effusion. Apart from the most frequent reasons of pericarditis and pericardial effusion, radiation induced, hypothyroid and primary manifestation of Hodgkin's disease equally arised. After repeated fenestration of the pericardium partial pericardiectomy was necessary. Chronic constrictive pericarditis was proved by the histological evaluation of the pericardial tissue that was probably provoked by the mediastinal irradiation. Since the pericardiectomy he has being well, he had no relapsed and no signs of pericardial fluid was observed. CONCLUSIONS: The early recognition and treatment of late complications are possible by the help of the patient's follow-up. These complications of Hodgkin's disease with using of modern radiotherapy apparatus are usually avoided.
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