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  • Title: Baseline susceptibility of primary human immunodeficiency virus type 1 to entry inhibitors.
    Author: Labrosse B, Labernardière JL, Dam E, Trouplin V, Skrabal K, Clavel F, Mammano F.
    Journal: J Virol; 2003 Jan; 77(2):1610-3. PubMed ID: 12502877.
    Abstract:
    Human immunodeficiency virus type 1 plasma viruses from 29 entry inhibitor-naive patients were characterized for their susceptibilities to T-20, AMD3100, and RANTES. A strikingly wide range of susceptibilities to T-20 was observed that was influenced by coreceptor usage but not by the susceptibilities of the viruses to inhibitors that target the chemokine receptors or by polymorphisms in the gp41 N helix.
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