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  • Title: [Linker histones: conformational changes and the role in the structural organization of chromatin].
    Author: Chikhirzhina EV, Vorob'ev VI.
    Journal: Tsitologiia; 2002; 44(8):721-36. PubMed ID: 12506665.
    Abstract:
    Histones, linker histones of the H1 family, their postsyntetic modifications, DNA-histone H1 interaction are reviewed. A question of protein change in spermatogenesis at the formation of inactive nucleus with high degree of DNA density is considered. Special attention was paid to sperm-specific histones of the H1 family of sperm cells. Their role in organization of high-order chromatin structure of sperm cells is discussed. Also, results of different studies on the structural organization of chromatin (nucleosomes, 30-nm fibers, chromatin loops and metaphase chromosomes) are discussed.
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