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  • Title: Linear scleroderma en coup de sabre and brain calcification: is there a pathogenic relationship?
    Author: Flores-Alvarado DE, Esquivel-Valerio JA, Garza-Elizondo M, Espinoza LR.
    Journal: J Rheumatol; 2003 Jan; 30(1):193-5. PubMed ID: 12508412.
    Abstract:
    Extracutaneous calcifications are rare in scleroderma and related conditions. We describe a female patient with linear scleroderma en coup de sabre and a longstanding clinical history of tonic and clonic convulsions. Radiographic study showed extensive cerebral calcifications in the right occipital hemisphere, homolateral to the involved side of her face. This report further suggests a relationship between localized scleroderma and neurological manifestations. Brain imaging studies should be routinely performed in scleroderma patients exhibiting neurological manifestations, especially seizure disorder.
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