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  • Title: [Trends in the nuclear-medical diagnosis of thrombosis].
    Author: Müller-Brand J, Fridrich R, Duckert F, Gruber UF, Schmitt HE.
    Journal: Schweiz Med Wochenschr; 1976 Jan 17; 106(3):78-81. PubMed ID: 1251158.
    Abstract:
    Use of the 125I-fibrinogen-uptake test for detection of freshly developing thrombi is well known. The administration of radiofibrinogen to detect preformed thrombus - the retrospective variant of the 125I-fibrinogen-uptake test - allows the diagnosis of established thrombosis. The correlation with ascending phlebography is 90%. 125I-Fibrinogen cannot be used for scanning, due to its low energy, while 131I-fibrinogen if used involves a high radiation dose to the patient. First experiments with new radiopharmaceuticals for detection of deep vein thrombosis are proposed. Indication lists for the retrospective variant of the 125I-fibrinogen-uptake test are given.
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