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  • Title: Occupational airways diseases from chronic low-level exposures to irritants.
    Author: Balmes JR.
    Journal: Clin Chest Med; 2002 Dec; 23(4):727-35, vi. PubMed ID: 12512162.
    Abstract:
    Short-term, high-level exposures to dusts, gases, mists, fumes, and smoke that are irritating to the respiratory tract are capable of inducing asthma, the so-called reactive airways dysfunction syndrome. Such exposures, however, do not occur frequently; chronic or recurrent exposures to lower levels of irritants are much more common. This article reviews the evidence that supports the concept that low-level exposures to respiratory tract irritants can contribute to the development of chronic obstructive pulmonary disease and asthma.
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