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  • Title: [The significance of postburn changes in plasma levels of ICAM-1, IL-10 and TNFalpha during early postburn stage in burn patients].
    Author: Kuang X, Ma K, Duan T.
    Journal: Zhonghua Shao Shang Za Zhi; 2002 Oct; 18(5):302-4. PubMed ID: 12515646.
    Abstract:
    OBJECTIVE: To observe the postburn changes in the plasma levels of ICAM-1, IL-10 and TNFalpha during early postburn stage. METHODS: Nineteen burn patients were enrolled in the study. The plasma levels of the above 3 kinds of factors were determined with ELISA in the peripheral plasma of the patients, plasma samples from 11 healthy volunteers were taken as the control. RESULTS: The plasma levels of ICAM-1, IL-10 and TNFalpha increased obviously postburn, especially in those patients who were complicated with hypovolumic shock, sepsis and MODS (P < 0.05 - 0.01). CONCLUSION: The monitoring of the postburn changes in plasma levels of ICAM-1, IL-10 and TNFalpha might be helpful in the forecast of postburn sepsis and the development of MODS.
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