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  • Title: [Osteoarticular allografts for repairing large bone or osteoarticular defects].
    Author: Sun L, Hu YY, Ning ZJ.
    Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2000 Nov; 14(6):377-9. PubMed ID: 12516445.
    Abstract:
    OBJECTIVE: To evaluate clinical outcome of bone or osteoarticular allografts. METHODS: From September 1991 to November 1997, large bone or osteoarticular defects secondary to bone tumors resection in 36 patients and severe trauma in 2 patients were repaired by deep frozen or lyophilized allogeneic osteoarticular or diaphysis graft. RESULTS: No obvious immune rejection to the grafts was observed in most of the patients in early stage after operation. The patients were followed up from 1 year and five months to 7 years and five months with an average of 4.2 years. Limb function was satisfactory in 74.19% of the 31 survival patients with large osteoarticular or diaphysis allografts. CONCLUSION: Cryopreserved or lyophilized allogeneic osteoarticular grafts with decreased antigenicity and good biocompatibility are suitable materials for repairing large bone or osteoarticular defects.
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