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Title: [Regression of hepatocellular carcinoma under Tamoxifen: report of one case and review of the literature]. Author: Macaigne G, Auriault ML, Boivin JF, Cheaib S, Chayette C, Deplus R. Journal: Gastroenterol Clin Biol; 2002 Dec; 26(12):1165-7. PubMed ID: 12520204. Abstract: Hepatocellular carcinoma is a malignant tumor with a poor prognosis, particularly when it is unresectable. The results of tamoxifen treatment in hepatocellular carcinoma have been disappointing and randomized studies have shown conflicting results. We report the case of a 72-yr-old-man with histologically confirmed hepatocellular carcinoma on a normal liver, that regressed with tamoxifen treatment. Regression was confirmed by normalization of serum alpha-fetoprotein levels and a significant decrease in radiological lesions by 66%. The patient was alive in excellent clinical condition more than 30 months after the initial diagnosis.[Abstract] [Full Text] [Related] [New Search]