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  • Title: Hydroxocobalamin therapy of cyanide intoxication in guinea pigs.
    Author: Posner MA, Tobey RE, McElroy H.
    Journal: Anesthesiology; 1976 Feb; 44(2):157-60. PubMed ID: 1252023.
    Abstract:
    The efficacy of hydroxocobalamin (vitamin B12a) as a specific, nontoxic antidote in acute cyanide poisoning was tested. Guinea pigs receiving lethal intravenous NaCN injections were treated with either vitamin B12a or saline solution. There was a statistically significant antidotal effect of the vitamin. No toxic effect was observed with large doses of the vitamin.
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