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  • Title: Detection of low-avidity immunoglobulin G in oral fluid samples: new approach for rubella diagnosis and surveillance.
    Author: Akingbade D, Cohen BJ, Brown DW.
    Journal: Clin Diagn Lab Immunol; 2003 Jan; 10(1):189-90. PubMed ID: 12522062.
    Abstract:
    Low-avidity rubella immunoglobulin G (IgG) was detected in oral fluid samples from 30 of 32 rubella IgM-positive patients (sensitivity, 94%) and from 4 of 34 IgM-negative patients (specificity, 88%). Measuring IgG avidity in oral fluid samples could improve the reliability of rubella surveillance when the incidence of the disease and the positive predictive value of IgM tests are low.
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