These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Daphcalycine, a novel heptacycle fused ring system alkaloid from Daphniphyllum calycinum.
    Author: Jossang A, El Bitar H, Pham VC, Sévenet T.
    Journal: J Org Chem; 2003 Jan 24; 68(2):300-4. PubMed ID: 12530852.
    Abstract:
    A novel Daphniphyllum alkaloid, daphcalycine (1), was isolated together with known daphnicyclidin D (2) from the stem bark of Daphniphyllum calycinum. The highly condensed polycyclic structure, established by spectral analysis, possessed an unusual framework: a central quinuclidine like tricycle produced by fusion of a piperidine, a tetrahydropyran, and an oxazine ring in turn condensed to surrounding three penta-, one hexa-, and one hepta-membered rings. The relative configuration of 11 carbon stereocenters of 1 was elucidated on the basis of NOESY.
    [Abstract] [Full Text] [Related] [New Search]