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  • Title: Effect of mifegin on the content of cyclic nucleotides in the cervical myometrium in full-term pregnancy.
    Author: Sergeev PV, Kareva EN, Gasparyan ND, Podval'nyuk VV.
    Journal: Bull Exp Biol Med; 2002 Oct; 134(4):349-50. PubMed ID: 12533756.
    Abstract:
    Cervical myometrium was examined in 22 pregnant women at 39-41 weeks gestation at risk of labor abnormalities. The patients received mifegin for preparing to labor. A new component in the mechanism of mifegin effect on the uterine cervix in full-term pregnancy was revealed: mifegin elevated the content of cAMP by 50% and almost 2-fold increased the cAMP/cGMP ratio compared to the initial level.
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