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  • Title: [Relationship between basic fibroblast growth factor (bFGF) and cell proliferation, invasion in pituitary adenoma].
    Author: Wen L, Chen L, Liu YS.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 2001 Oct 28; 26(5):466-8. PubMed ID: 12536505.
    Abstract:
    Basic fibroblast growth factor (bFGF) and proliferating cell nuclear antigen (PCNA) were examined by immunohistochemistry in fifty-one pituitary adenomas. The results showed that the intensity of bFGF expression was strong or intermediate in twenty-nine adenomas, which was positively related to cell proliferation, there was positive relationship between bFGF expressin and tumor invasion in non-functional adenomas. The data suggest that bFGF may play some role in the origin and progression of pituitary adenomas.
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