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  • Title: [Clinical study of the effect of buflomedil on peripheral neuropathy in diabetic patients].
    Author: Zhou M, Lei MX.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 2001 Jun 28; 26(3):239-40. PubMed ID: 12536693.
    Abstract:
    OBJECTIVE: To observe the effect of buflomedil on clinical symptom and nerve conduction velocity (NCV) of diabetic peripheral neuropathy patients. METHODS: 58 cases of diabetic patents with peripheral neuropathy were divided into diabetes group treated with buflomedil (DB) 100 mg.d-1 and diabetes control group (DP) treated with PGE1 200 micrograms.d-1. NCV was measured and peripheral nerve symtom was observed in two groups before treatment and after 2 weeks. RESULTS: NCV and peripheral nerve symptom were obviously improved both in DB group and DP group (P < 0.01). The effective rate were respectively 80.0% and 89.3% in DB group and DP group. The diversity was no significant in DB group and DP group (P > 0.05). CONCLUSION: buflomedil is an effective and safe drug for treating diabetic peripheral neuropathy patients.
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