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  • Title: [Effects of monoclonal antibody against the major cell surface protein on salivary agglutinin mediated aggregation of Streptococcus sobrinus].
    Author: Zhang P, Fan M, Bian Z.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 1999 Aug; 17(3):221-3. PubMed ID: 12539288.
    Abstract:
    OBJECTIVE: To investigate the effects of monoclonal antibody on salivary agglutinin-mediated aggregation of Streptococcus sobrinus in vitro. METHODS: Bacterial aggregation inhibition was measured under OD650 at 10 minutes intervals for 1 hour. RESULTS: It showed that the McAb ZS2/286 raised against the PAg of S. sobrinus 6715 could inhibit the aggregation by some degree, but the effect was not significant. CONCLUSION: The McAb ZS2/286 might not bind directly to the functionally important region of PAg related to aggregation.
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