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  • Title: [Application of intravenous and inhalational combined anesthesia with midazolam, fentanyl 1 and enflurane in cleft palate repair operation].
    Author: Wang X, Bai H, Shu L.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 1999 Aug; 17(3):239-41. PubMed ID: 12539294.
    Abstract:
    OBJECTIVE: To observe the effects of intravenous and inhalational combined anesthesia with midazolam, fetanyl l and enflurane in the cleft palate repair operation. METHODS: 128 patients prepared for cleft palate repair operation were selected randomly. Anesthesia was induced with 0.2-0.3 mg/kg midazolam, 3-5 micrograms/kg fentanyl 1, and intubation was facilitated with 1-2 mg/kg succinylcholine. Anesthesia was maintained with fentanyl 1 and enflurane, and changes of hemodynamics and incident rates of hiccup, cough and vomit were observed during and after operation. RESULTS: 1. After inducing, systolic pressure (SP) was decreased by 5%-8%, diastolic pressure (DP) decreased by 8%-10%(P < 0.05), and there were no significant changes in heart rates (HR) (P > 0.05). After intubation, there were no significant changes in SP, DP and HR. 2. After induction, the incident rates of hiccup and cough were 3.1% and 7.8% respectively. After operation, the incident rate of vomit was 7.0%. 3. The volume of lost blood was 5% less than the patient's whole blood volume. CONCLUSION: The anesthetic way is easy to be controlled with few side effects, and patients can revive easily, so it is a safe, efficient and perfect way in cleft palate repair operation.
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