These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effects of mechanical stretch on collagen type I and total protein synthesis of human periodontal ligament fibroblasts].
    Author: Chen X, Han W, Zhao Y.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 2001 Jun; 19(3):155-7. PubMed ID: 12539400.
    Abstract:
    OBJECTIVE: The aim of this study is to investigate the effects of mechanical stretch on type I collagen and total protein synthesis of human periodontal ligament fibroblasts (PDLFs). METHODS: Enzyme link immunosorbent assay (ELISA) and Coomassie brilliant blue stain method were used to examine the anabolism of PDLFs growing on the flexible culture plates subjected to mechanical stretch. The five loading devices of PDLFs were designed and the stain varied from 1% to 8%. RESULTS: Mechanical stretch had no effect on type I collagen synthesis. However, in the range of 1% to 8% of stretch, the protein synthesis was reduced. The mechanical stretching of 2% strain affected the protein synthesis most obviously. CONCLUSION: Mechanical stretch can modify the composition of extracellular matrix of PDLFs.
    [Abstract] [Full Text] [Related] [New Search]