These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Manometric studies on the human pyloric sphincter. Effect of cigarette smoking, metoclopramide, and atropine.
    Author: Valenzuela JE, Defilippi C, Csendes A.
    Journal: Gastroenterology; 1976 Apr; 70(4):481-3. PubMed ID: 1254134.
    Abstract:
    Pyloric sphincter pressure was assessed with water-perfused polyvinyl tubes. Smoking one cigarette significantly decreased the basal pyloric pressure, whereas 10 mg of metoclopramide as an intravenous bolus increased the pyloric pressure in normal subjects and in patients with gastric ulcer with low basal pressure. Duodenal acidification with 0.1 N HCl significantly increased pyloric pressure. Atropine 15 mug per kg, subcutaneously prevented the rise of pyloric pressure in response to acid infusion into the duodenum.
    [Abstract] [Full Text] [Related] [New Search]