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  • Title: Neonatal lupus erythematosus with recurrent pancytopenia: a case report.
    Author: Wang LJ, Yang YH, Lin MI, Chiang BL, Mu SC.
    Journal: J Microbiol Immunol Infect; 2002 Dec; 35(4):262-4. PubMed ID: 12542254.
    Abstract:
    Neonatal lupus erythematosus is an immune-mediated disease associated with the transplacental passage of maternal autoantibodies, primarily anti-Ro (SS-A) and anti-La (SS-B). The major clinical manifestations are isolated congenital heart block and cutaneous lupus lesions. Other symptoms include hematologic and hepatic abnormalities. We report a male neonate, born to a mother with Sjögren's syndrome, who experienced cutaneous lupus lesions and 2 episodes of pancytopenia. Both anti-Ro and anti-La antibodies were positive in infant and mother.
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